From Basic Research to Clinical Practice
Cooperation between HI-STEM and Heidelberg University Hospital Departments
Heidelberg University Hospital Departments
Medical Clinic V - Hematology – Oncology – Rheumatology
Prof. Dr. Anthony Ho, Medical Director, Project partner of HI-STEM in the BMBF Top Cluster Program
Professor Ho is one of HI-STEM's privileged clinical partners. A group of young scientists will be conducting research in Prof. Ho's laboratory facilities. This cooperation serves to further optimize and connect the collaboration between cutting edge clinical and basic research.
Department of Urology
Professor Dr. med. Markus Hohenfellner, Medical Director
The goal of this cooperation is to identify and combat prostate cancer stem cells. Dr. Thomas Höfner, a surgeon on Prof. Hohenfellner's staff, is currently analyzing tumor samples at HI-STEM using modern molecular techniques.
Prof. Dr. Andreas Schneeweiss, Dr. Frederik Marmé, Head of the Working Group, and Prof. Dr. Barbara Burwinkel
This group is conducting a large-scale study in which metastatic cancer stem cells in blood samples from 600 breast cancer patients will be measured and studied by molecular analysis. In a second study, investigators will search for cancer stem cells in ovarian tumors.
Department of General, Visceral and Transplantation Surgery
Prof. Dr. med. Jens Werner, MBA,
First Senior Physician and Director of the Pancreatic Surgery Unit
The goal of this study is to decipher the reasons for the rapid metastasis of pancreatic cancer to the liver and to tackle this problem
Mannheim University Hospital
Medical Clinic III – Hematology and Internal Oncology
Prof. Dr. med. Wolf-K. Hofmann, Director
These investigators are investigating a murine model of myelodysplastic syndrome, a form of blood cancer. The goal is to gain a better understanding of the cellular and biological causes of this type of cancer, which originates in stem cells, in order to better treat the disease.
Department of Dermatology, Venerology and Allergology
Dr. Jochen Utikal
In this collaboration, researchers will investigate the role of cancer gene Myc in the reprogramming of skin cells into induced pluripotent stem cells (iPS cells).
Jena University Hospital
Clinic for Internal Medicine II -Department of Hematology and Internal Oncology
Prof. Dr. med. Andreas Hochhaus, Director of the Department
In this planned study of patients with chronic myelogenous leukemia (CML), researchers will soon investigate whether leukemia stem cells can be killed by successive combina- tion treatments consisting of interferons and tyrosine kinase inhibitors. If successful, this treatment could result in cure.
Düsseldorf University Hospital
Prof. Dr. Rainer Haas, Director
In this project, the effects of multiple myeloma cells in patient samples on stem cell niches will be investigated using innovative murine models.