Research Group Experimental Hematology

Mick Milsom
Senior Group Leader

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1. Walter D., Lier A, Geiselhart A., Thalheimer F.B., Huntscha S., Sobotta M.C., Moehrle B., Brocks D., Bayindir I., Kaschutnig P., Müdder K., Klein C., Jauch A., Schroeder T., Geiger H., Dick T.P., Holland-Letz T., Schmezer P., Lane S.W., Rieger M.A., Essers M.A.G., Williams D.A.W., Trumpp A.and Milsom M.D. (2015). Exit from dormancy provokes DNA damage-induced attrition in haematopoietic stem cells. Nature, 520(7548): pp549-552).

2. Cabezas-Wallscheid N., Klimmeck D., Hansson J., Lipka D.B., Reyes A., Wang Q., Weichenhan D., Lier A., von Paleske L., Renders S., Wünsche P., Brocks D., Gu L., Herrmann C., Haas S., Essers M., Brors B., Eils R., §Huber W., §Milsom M.D., §Plass C., §Krijgsveld J. and §Trumpp A. (2014). Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome and DNA methylome analysis. Cell Stem Cell, 15(4): pp507-522.§Shared senior authorship.

3. Kaschutnig P., Bogeska R., Walter D., Lier A., Huntscha S. and Milsom M.D. (2015). The Fanconi anemia pathway is required for efficient repair of stress-induced DNA damage in hematopoietic stem cells. Cell Cycle, 14(17): pp2734-2742.

4. Lipka D.B., Wang Q., Cabezas-Wallscheid N, Klimmeck D, Weichenhan D., Herrmann C, Lier A., Brocks D., Assenov Y., von Paleske L., Renders S., Wünsche P., Zeisberger P., Gu L., Haas S., Essers M.A.G, Brors B, Eils R., §Trumpp A, §Milsom M.D., and §Plass C. (2014). Identification of DNA methylation changes at cis-regulatory elements during early steps of HSC differentiation using tagmentation-based whole genome bisulphite sequencing. Cell Cycle, 13(22): pp3476-3487.§Shared senior authorship

5. Haas S., Hansson J., Klimmeck D., Löffler D., Velten L., Uckelmann H., Wurzer S., Prendergast A., Schnell A., Hexel K., Santarella-Mellwig R.,Blaszkiewicz S., Kuck A., Geiger H., Milsom M.D., Steinmetz L., Schroeder T., Trumpp A., Krijgsveld J. and Essers M.A.G. (2015). Inflammation-induced emergency megakaryopoiesis driven by hematopoietic stem cell-like megakaryocyte progenitors. Cell Stem Cell, 17(4): pp422-434.

6. Placke T., Faber K., Nonami A., Putwain S., Salih H., Heidel F., Krämer A., Root D., Barbie D., Armstrong S., Hahn W., Huntly B., Sykes S., Milsom M.D., Scholl C. and Fröhling S. (2014). Requirement for CDK6 in MLL-rearranged acute myeloid leukemia. Blood, 124 (1): pp13-23