Research Group Normal and Malignant Stem Cells

Andreas Trumpp
Group Leader



I. Highlight Publications

February 14, 2019

The long non-coding RNA Meg3 is dispensable for hematopoietic stem cells (Scientific Reports, 2019)

Sommerkamp, P., Renders, S., Ladel, L., Hotz-Wagenblatt, A., Schönberger, K., Zeisberger, P., Przybylla, A., Sohn, M., Zhou, Y., Klibanski, A., Cabezas-Wallscheid, N.@, & Trumpp, A.@ (2019). The long non-coding RNA Meg3 is dispensable for hematopoietic stem…
December 20, 2018

Identification of Embryonic Neural Plate Border Stem Cells and Their Generation by Direct Reprogramming from Adult Human Blood Cells (Cell Stem Cell, 2019)

Thier, M.C., Hommerding, O., Panten, J., Pinna, R., Garcia-Gonzalez, D., Berger, T., Worsdorfer, P., Assenov, Y., Scognamiglio, R., Przybylla, A., Kaschutnig, P., Becker, L., Milsom, M.D., Jauch, A., Utikal, J., Herrmann, C., Monyer, H., Edenhofer, F., &…
January 17, 2018

A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies (Nature, 2018)

Bahr C*, von Paleske L*, Uslu VV*, Remeseiro S, Takayama N, Ng SW, Murison A, Langenfeld K, Petretich M, Scognamiglio R, Zeisberger P, Benk A, Amit I, Zandstra PW, Lupien M, Dick JE, Trumpp A @ and Spitz F @ (2018). "A cluster of distal Myc enhancers…
November 10, 2017

BCAT1 restrictsαKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation (Nature, 2017)

Raffel S, Falcone M, Kneisel N, Hansson J, Wang W, Lutz C, Bullinger L, Poschet G, Nonnenmacher Y, Barnert A, Bahr C, Zeisberger P, Przybylla A, Sohn M, Tönjes M, Erez A, Adler L, Jensen P, Scholl C, Fröhling S, Cocciardi S, Wuchter P, Thiede C, Flörcken A,…
May 18, 2017

Vitamin A-Retinoic Acid Signaling Regulates Hematopoietic Stem Cell Dormancy (Cell, 2017)

Cabezas-Wallscheid N, Buettner F, Sommerkamp P, Klimmeck D, Ladel L, Thalheimer FB, Pastor-Flores D, Roma LP, Renders S, Zeisberger P, Przybylla A, Schönberger K, Scognamiglio R, Altamura S, Florian CM, Fawaz M, Vonficht D, Tesio M, Collier P, Pavlinic 8,…
March 20, 2017

Human haematopoietic stem cell lineage commitment is a continuous process (Nature Cell Biology, 2017)

Velten L, Haas SF, Raffel S, Blaszkiewicz S, Islam S, Hennig BP, Hirche C, Lutz C, Buss EC, Nowak D, Boch T, Hofmann WK, Ho AD, Huber W, Trumpp A, Essers MA, Steinmetz LM (2017). "Human haematopoietic stem cell lineage commitment is a continuous process."…

Myc Depletion Induces a Pluripotent Dormant State Mimicking Diapause (Cell, 2016)

Feb 16, 2016
Scognamiglio R, Cabezas-Wallscheid N, Thier MC, Altamura S, Reyes A, Prendergast ÁM,…

Awakening dormant haematopoietic stem cells (Nature Reviews Immunology, 2010)

Mar 01, 2010
Trumpp, A., Essers, M., & Wilson, A. (2010). Awakening dormant haematopoietic stem cells.…

IFNalpha activates dormant haematopoietic stem cells in vivo (Nature, 2009)

Apr 16, 2009
Essers MA, Offner S, Blanco-Bose WE, Waibler Z, Kalinke U, Duchosal MA, Trumpp A (2009).…

Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair (Cell, 2008)

Dec 12, 2008
Wilson A, Laurenti E, Oser G, van der Wath RC, Blanco-Bose W, Jaworski M, Offner S,…

Hematopoietic Stem Cell Function and Survival Depend on c-Myc and N-Myc Activity (Cell Stem Cell, 2008)

Dec 04, 2008
Laurenti E, Varnum-Finney B, Wilson A, Ferrero I, Blanco-Bose WE, Ehninger A, Knoepfler…

II. All Publications

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