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Metastasis-initiating cells induce and exploit a fibroblast niche to fuel malignant colonization of the lungs (Nature Communications, 2020)

Lung metastasis in a breast cancer patient: the arrows indicate fibroblasts (brown) that communicate with metastatic cancer cells. Cell nuclei are stained blue. © Oskarsson, DKFZ/HI-STEM
Lung metastasis in a breast cancer patient: the arrows indicate fibroblasts (brown) that communicate with metastatic cancer cells. Cell nuclei are stained blue. © Oskarsson, DKFZ/HI-STEM

Pein, M., Insua-Rodríguez, J., Hongu, T., Riedel, A., Meier, J., Wiedmann, L., Decker, K., Essers, M. A. G., Sinn, H. P., Spaich, S., Sutterlin, M., Schneeweiss, A., Trumpp, A. and Oskarsson, T. (2020). Metastasis-initiating cells induce and exploit a fibroblast niche to fuel malignant colonization of the lungs. Nature Communications, 11(1), 1494. DOI: 10.1038/s41467-020-15188-x

Feature in at Ärzteblatt.de: https://www.aerzteblatt.de/nachrichten/111618/Strategien-von-Tumorzellen-zur-Metastasenbildung

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