In bone sections a strong increase in the number of polyploid megakaryocytes (red cells) was observed after treatment of mice with IFN

Haas S, Hansson J, Klimmeck D, Loeffler D, Velten L, Uckelmann H, Wurzer S, Prendergast ÁM, Schnell A, Hexel K, Santarella-Mellwig R, Blaszkiewicz S, Kuck A, Geiger H, Milsom MD, Steinmetz LM, Schroeder T, Trumpp A, Krijgsveld J, Essers MA (2015). "Inflammation-induced emergency megakaryopoiesis driven by hematopoietic stem cell-like megakaryocyte progenitors." Cell stem cell, 17(4), 422-434. https://doi.org/10.1016/j.stem.2015.07.007

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