Solid Tumors and Metastasis

Solid Tumors, Metastasis & Therapy Resistance

Read more
Solid Tumors and Metastasis
Hematopoietic Stem Cells and Leukemia

Hematopoietic Stem Cells and Leukemia

Read more
Hematopoietic Stem Cells and Leukemia
Stem Cells and Tumor Microenvironment

Stem Cells and Tumor Microenvironment

Read more
Stem Cells and Tumor Microenvironment
The HI-STEM Team

The HI-STEM Team

HI-STEM features an interdisciplinary research team.
The HI-STEM Team
HI-STEM Group Leaders

HI-STEM Group Leaders

HI-STEM Group Leaders
Movie Slide

Watch the HI-STEM Movie!

Movie Slide
PlayPause
previous arrow
next arrow

Stress signaling in breast cancer cells induces matrix components that promote chemoresistant metastasis (EMBO Molecular Medicine, 2018)

Graphical abstract describing the link between JNK activity and metastasis prevalence in breast cancer

Insua-Rodríguez J, Pein M, Hongu T, Meier J, Descot A, Lowy CM, De Braekeleer E, Sinn HP, Spaich S, Sütterlin M, Schneeweiss A, Oskarsson T (2018). "Stress signaling in breast cancer cells induces matrix components that promote chemoresistant metastasis" EMBO molecular medicine, e9003. doi: 10.15252/emmm.201809003

Further Reading:

HI STEM researchers show link between stress signaling and chemotherapy resistant metastasis in breast cancer

Links and further information

Pubmed | Read at Publisher
DKFZ Press Release
DKFZ Pressemitteilung (deutsch)