Slide 1
Research Group Pattern Recognition
and Digital Medicine

Daniel Hübschmann
Group Leader

The group focuses on method development and application of pattern recognition algorithms, both supervised and unsupervised. Tools and software, originating from both own development and external colleagues, are applied to high dimensional data sets, which were often, but not exclusively generated by high throughput and omics technologies (genomics, transcriptomics, different epigenetic readouts). A majority of the data originates from cancer samples or sequencing projects, but the developed software has also been successfully applied to data generated from non-neoplastic biological specimen.

Keywords: Bioinformatics, single cell, multi-omics integration, personalized oncology

Daniel Hübschmann giving a talk on Homologous recombination, BRCAness and the TOP-ART trial @ ITN CONTRA - Computational Cancer Research in 2019:

Scientific Software


YAPSA is an R package providing functionality for supervised pattern recognition with a special focus on analysis of mutational signatures:


Bratwurst is a software designed for unsupervised or semi-supervised pattern recognition with non-negative matrix factorization (NMF).

  • Software repository:
  • Citation: Steinhauser, S.* and Hübschmann, D.* (2016). Bratwurst: preprocessing, wrappers and downstream analysis for NMF. R package version 1.0
River Plot
River Plot showing hierarchy of signatures extracted by NMF


The group Pattern Recognition and Digital Medicine is looking for interested PhD, Master and Bachelor students. If you are interested please contact This email address is being protected from spambots. You need JavaScript enabled to view it..