The German Research Foundation (DFG) will support the new Collaborative Research Center (SFB) 1709 “Cellular Plasticity in Malignant Myeloid Diseases – From Mechanism to Therapy” over the next four years. In around 20 working groups, scientists will investigate how and why certain leukemia cells change during the course of the disease and during therapy. The aim is to break their resistance to therapy in the future or prevent it from developing in the first place. HI-STEM managing director Prof. Dr. Andreas Trumpp is co-speaker of the collaborative research center and three HI-STEM group leaders are contributing to it with individual projects.