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      • Prof. Dr. Andreas Trumpp

        Prof. Dr. Andreas Trumpp

        Dr. Marieke Essers

        Dr. Marieke Essers

        Dr. Michael Milsom

        Dr. Michael Milsom

        Dr. Martin Sprick

        Dr. Martin Sprick

        Dr. Marc Thier

        Dr. Marc Thier

        Dr. Simon Haas

        Dr. Simon Haas

        Dr. Dr. Daniel Hübschmann

        Dr. Dr. Daniel
        Hübschmann

        Dr. Rene Jackstadt

        Dr. Rene Jackstadt

        Dr. Hamed Alborzinia

        Dr. Hamed Alborzinia

  • Research
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      • Normal & Malignant
        Stem Cells

        Normal & Malignant  Stem Cells
        Head:
        Prof. Dr. Andreas Trumpp

        Experimental
        Hematology

        Experimental Hematology
        Head:
        Dr. Mick Milsom

        Inflammatory Stress
        in Stem Cells

        Inflammatory Stress in Stem Cells
        Head:
        Dr. Marieke Essers

        Pattern Recognition &
        Digital Medicine


        Pattern Recognition & Digital Medicine
        Head:
        Dr. Dr. Daniel Hübschmann

        Stem Cells at the
        Interface of
        Hematopoiesis,
        Immunity & Cancer

        Stem Cells at the Interface of Hematopoiesis, Immunity & Cancer
        Head:
        Dr. Simon Haas

        Neural
        Reprogramming
        and Clinical
        Translation

        Neural Reprogramming and Clinical Translation
        Head:
        Dr. Marc Thier

        Stem Cells and
        Metastases

        Stem Cells and Metastases
        Head:
        Dr. Martin Sprick
        Prof. Dr. Andreas Trumpp

        Cancer Progression
        and Metastasis


        Cancer Progression  and Metastasis
        Head:
        Dr. Rene Jackstadt
      • Normal and Malignant Stem Cells
      • Experimental Hematology
      • Stem Cells and Metastases
      • Neural Reprogramming and Clinical Translation
      • Pattern Recognition
      • Stem Cells at the Interface of hematopoiesis, Immunity and Cancer
      • Stress Induced Activation of Hematopoietic Stem Cells
      • Cancer Progression and Metastasis
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  • Defective homologous recombination DNA repair as therapeutic target in advanced chordoma (Nature Communications, 2019)

  • Genomic and transcriptomic changes complement each other in the pathogenesis of sporadic Burkitt lymphoma (Nature Communications, 2019)

  • Mutational patterns and regulatory networks in epigenetic subgroups of meningioma (Acta Neuropathologica, 2019)

HI-STEM Movie

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News

June 03, 2025

HI-STEM Group Leaders part of the new DFG funded collaborative research center for blood cancer

The German Research Foundation (DFG) will support the new Collaborative Research Center (SFB) 1709 “Cellular Plasticity in Malignant Myeloid Diseases – From Mechanism to Therapy” over the next four years. In around 20 working groups, scientists will…
Jun 03, 2025

Mirco Friedrich at the Forbes List "30 under 30 Europe"

Mirco Julian Friedrich, Junior Group Leader at HI-STEM, DKFZ and Heidelberg University…
Nov 07, 2023

Congratulations to Michael Milsom!

With his publication "Inflammatory exposure drives long-lived impairment of hematopoietic…
Jun 16, 2023

Oral presentation at the European Hematology Association annual meeting. Ian Ghezzi presented his PhD work on the role of cancer stem cell dormancy in disease propagation and therapy resistance of JAK2-mutated MPNs at the annual meeting of the European He

Jun 16, 2023

Congratulations to Lena Bognar, who was awarded a DKFZ Graduate School Stipend to fund her PhD studies within the group, focussed on the role of EVI1 in modulating the cellular DNA damage response.

HI-STEM is supported by:

  • German Cancer Reseach Center (DKFZ) Heidelberg
  • Dietmar Hopp Stiftung

Interesting Links

  • Heidelberg University Hospital
  • Mannheim University Hospital
  • National Center for Tumor Diseases Heidelberg

Contact

HI-STEM gGmbH
Im Neuenheimer Feld 280
69120 Heidelberg
Tel: +49 6221 42-3901
office-trumpp@dkfz-heidelberg.de

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