Marc Christian Thier, Oliver Hommerding, Jasper Panten, Roberta Pinna, Diego García-González, Thomas Berger, Philipp Wörsdörfer, Yassen Assenov, Roberta Scognamiglio, Adriana Przybylla, Paul Kaschutnig, Lisa Becker, Michael D. Milsom, Anna Jauch, Jochen Utikal, Carl Herrmann, Hannah Monyer, Frank Edenhofer & Andreas Trumpp. Identification of Embryonic Neural Plate Border Stem Cells and their generation by direct reprogramming from human blood. CELL Stem Cell. 2019 Jan 3;24(1):166-182.e13. doi: 10.1016/j.stem.2018.11.015

 

Paul Kaschutnig, Irem Bayindir-Buchhalter, Marc Thier, Wiebke Nadler, Sabrina Hanke, Stella Paffenholz, Milena Block, Ruzhica Bogeska, David Hills, Andreas Trumpp, Christoph Rösli, Alexander Medvinsky, Michael Milsom. Functional and molecular segregation of in vitro specified hematopoietic stem and progenitor cells using a HOXB4 knock-in reporter. Exp. Hematol. VOLUME 44, ISSUE 9, SUPPLEMENT , S84, SEPTEMBER 01, 2016.https://doi.org/10.1016/j.exphem.2016.06.169

 

Scognamiglio R, Cabezas-Wallscheid N, Thier MC, Altamura S, Reyes A, Prendergast ÁM, Baumgärtner D, Carnevalli LS, Atzberger A, Haas S, von Paleske L, Boroviak T, Wörsdörfer P, Essers MA, Kloz U, Eisenman RN, Edenhofer F, Bertone P, Huber W, van der Hoeven F, Smith A, Trumpp A. Myc Depletion Induces a Pluripotent Dormant State Mimicking Diapause. Cell. 2016 Feb 11;164(4):668-80. https://doi.org/10.1016/j.cell.2015.12.033

 

Münst B*, Thier MC*, Winnemöller D*, Helfen M, Thummer RP, Edenhofer F. Nanog induces suppression of senescence via down-regulation of p27KIP1 expression. *Authors contributed equally. J Cell Sci. 2016 Mar 1;129(5):912-20. https://doi.org/10.1242/jcs.167932.

 

Bung R*, Wörsdörfer P*, Thier MC*, Vogt K, Gebhardt M, Edenhofer F. Partial dedifferentiation of murine radial glia type neural stem cells by Brn2 and c-Myc yields early neuroepithelial progenitors. *Authors contributed equally.  J Mol Biol. 2016 Apr 10;428(7):1476-83. https://doi.org/10.1016/j.jmb.2015.10.028

 

Meyer S, Wörsdörfer P, Günther K, Thier M, Edenhofer F. Derivation of Adult Human Fibroblasts and their Direct Conversion into Expandable Neural Progenitor Cells. J Vis Exp. 2015 Jul 29;(101):e52831. https://doi.org/10.3791/52831.

 

Kim BM, Thier MC, Oh S, Sherwood R, Kanellopoulou C, Edenhofer F, Choi MY. MicroRNAs are indispensable for reprogramming mouse embryonic fibroblasts into induced stem cell-like cells. PLoS One. 2012;7(6):e39239. https://doi.org/10.1371/journal.pone.0039239

 

Thier M, Münst B, Mielke S, Edenhofer F. Cellular reprogramming employing recombinant sox2 protein. Stem Cells Int. 2012;2012:549846. https://doi.org/10.1155/2012/549846

 

Haupt, S., J. Grützner, M.-C. Thier, F. Edenhofer, B. H. Rath, I. Laufenberg., M. Forgber, J. Eberhardt & O. Brüstle, Automated selection and harvesting of pluripotent stem cell colonies. Biotechnol Appl Biochem. 2012 Mar-Apr;59(2):77-87. https://doi.org/10.1002/bab.1014

 

Thier*, Philipp Wörsdörfer*, Yenal Bernhard Lakes*, Raphaela Gorris, Stefan Herms, Thoralf Opitz, Dominic Seiferling, Tamara Quandel, Per Hoffmann, Markus Nöthen, Oliver Brüstle, and Frank Edenhofer. Direct Conversion of Fibroblasts into Stably Expandable Neural Stem Cells. CELL Stem Cell. 2012 Apr 6;10(4):473-9. https://doi.org/10.1016/j.stem.2012.03.003

 

Thier, B. Münst, F Edenhofer. Exploring refined conditions for reprogramming cells by recombinant Oct4 protein. International Journal of Developmental Biology. Int J Dev Biol. 2010;54(11-12):1713-21. https://doi.org/10.1387/ijdb.103193mt

 

Reviews:

Wörsdörfer P*, Thier M*, Kadari A*, Edenhofer F. Roadmap to cellular reprogramming - manipulating transcriptional networks with DNA, RNA, proteins and small molecules. *Authors contributed equally. Curr Mol Med. 2013 Jun;13(5):868-78 https://doi.org/10.2174/1566524011313050017 

Bosnali*, B. Münst*, M. Thier*, F. Edenhofer. Deciphering the stem cell machinery as a basis for understanding the molecular mechanism underlying reprogramming. *Authors contributed equally. Cell Mol Life Sci. 2009 Nov;66(21):3403-20. https://doi.org/10.1007/s00018-009-0095-2