Solid Tumors and Metastasis

Solid Tumors, Metastasis & Therapy Resistance

Solid Tumors and Metastasis
Hematopoietic Stem Cells and Leukemia

Hematopoietic Stem Cells and Leukemia

Hematopoietic Stem Cells and Leukemia
Stem Cells and Tumor Microenvironment

Stem Cells and Tumor Microenvironment

Stem Cells and Tumor Microenvironment
HI-STEM Group Leaders

HI-STEM Group Leaders

HI-STEM Group Leaders
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Sommerkamp, P., Romero-Mulero, M. C., Narr, A., Ladel, L., Hustin, L., Schonberger, K., Renders, S., Altamura, S., Zeisberger, P., Jacklein, K., Klimmeck, D., Rodriguez-Fraticelli, A., Camargo, F. D., Perie, L., Trumpp, A. & Cabezas-Wallscheid, N. (2021) Mouse multipotent progenitor 5 cells are located at the interphase between hematopoietic stem and progenitor cells, Blood. 137, 3218-3224. https://doi.org/10.1182/blood.2020007876

 

Velten, L., Story, B.A., Hernandez-Malmierca, P., Raffel, S., Leonce, D.R., Milbank, J., Paulsen, M., Demir, A., Szu-Tu, C., Fromel, R., Lutz, C., Nowak, D., Jann, J.C., Pabst, C., Boch, T., Hofmann, W.K., Muller-Tidow, C., Trumpp, A., Haas, S., & Steinmetz, L.M. (2021). Identification of leukemic and pre-leukemic stem cells by clonal tracking from single-cell transcriptomics. Nature Communications, 12(1), 1366. doi: 10.1038/s41467-021-21650-1

Renders, S., Svendsen, A. F., Panten, J., Rama, N., Maryanovich, M., Sommerkamp, P., Ladel, L., Redavid, A. R., Gibert, B., Lazare, S., Ducarouge, B., Schönberger, K., Narr, A., Tourbez, M., Dethmers-Ausema, B., Zwart, E., Hotz-Wagenblatt, A., Zhang, D., Korn, C., Zeisberger, P., Przybylla, A., Sohn, M., Mendez-Ferrer, S., Heikenwälder, M., Brune, M., Klimmeck, D., Bystrykh, L., Frenette, P. S., Mehlen, P., de Haan, G., Cabezas-Wallscheid, N.*, & Trumpp, A.* (2021). Niche derived netrin-1 regulates hematopoietic stem cell dormancy via its receptor neogenin-1. Nature Communications, 12(1), 608. 10.1038/s41467-020-20801-0

Espinet, E.@, Gu, Z., Imbusch, C.D., Giese, N.A., Buscher, M., Safavi, M., Weisenburger, S., Klein, C., Vogel, V., Falcone, M., Insua-Rodriguez, J., Reitberger, M., Thiel, V., Kossi, S.O., Muckenhuber, A., Sarai, K., Lee, A.Y., Backx, E., Zarei, S., Gaida, M.M., Rodriguez-Paredes, M., Donato, E., Yen, H.Y., Eils, R., Schlesner, M., Pfarr, N., Hackert, T., Plass, C., Brors, B., Steiger, K., Weichenhan, D., Arda, H.E., Rooman, I., Kopp, J.L., Strobel, O., Weichert, W., Sprick, M.R.*, & Trumpp, A.@* (2020). Aggressive PDACs show hypomethylation of repetitive elements and the execution of an intrinsic IFN program linked to a ductal cell-of-origin. Cancer Discovery. doi: 10.1158/2159-8290.CD-20-1202 *: Shared last authorship, @: corresponding authors