Clonal hematopoiesis landscape in frequent blood donors

Karpova D, Huerga Encabo H, Donato E, Calderazzo S, Scherer M, Llorian-Sopena M, Leppä AM, Würth R, Stelmach P, Papazoglou D, Ferrelli A, Ngo S, Kotova I, Harenkamp S, Zimmer K, Wolf D, Panten J, Reed J, Przybylla A, Tonn T, Kopp-Schneider A, Velten L, DiPersio JF, Wong TN, Bonnet D, Bonig H, Trumpp A.

7-Dehydrocholesterol is an endogenous suppressor of ferroptosis.

Freitas FP, Alborzinia H, Dos Santos AF, Nepachalovich P, Pedrera L, Zilka O, Inague A, Klein C, Aroua N, Kaushal K, Kast B, Lorenz SM, Kunz V, Nehring H, Xavier da Silva TN, Chen Z, Atici S, Doll SG, Schaefer EL, Ekpo I, Schmitz W, Horling A, Imming P, Miyamoto S, Wehman AM, Genaro-Mattos TC, Mirnics K, Kumar L, Klein-Seetharaman J, Meierjohann S, Weigand I, Kroiss M, Bornkamm GW, Gomes F, Netto LES, Sathian MB, Konrad DB, Covey DF, Michalke B, Bommert K, Bargou RC, Garcia-Saez A, Pratt DA, Fedorova M, Trumpp A, Conrad M, Friedmann Angeli JP. Nature. 2024 Feb;626(7998):401-410.

Our paper is highlighted in:

https://intranet.dkfz.de/artikel/cholesterin-vorstufe-schuetzt-krebszellen-vor-zelltod-und-macht-sie-aggressiver

https://aacrjournals.org/cdnews/news/1288/7-Dehydrocholesterol-Suppresses-Ferroptosis-and

Bouman BJ, Demerdash Y, Sood S, Grünschläger F, Pilz F, Itani AR, Kuck A, Marot-Lassauzaie V, Haas S, Haghverdi L, Essers MA.

Single-cell time series analysis reveals the dynamics of HSPC response to inflammation.

Life Sci Alliance. 2023 Dec 18;7(3):e202302309. doi: 10.26508/lsa.202302309. Print 2024 Mar.PMID: 38110222